To make a Lizard in Little Alchemy 2, you will need to combine both Air and Reptile. The order in which you combine these elements does not matter, so you can start with either one.
First, begin by dragging the Air element onto the playing board. Then, drag the Reptile element onto the playing board. Once both elements are on the board, the game will recognize the combination and automatically create the Lizard.
The new Lizard element can now be used to combine with other items to create more new elements. For example, you can combine the Lizard with Water to create an Alligator. Alternatively, you can also combine the Lizard and Plant to create a Chameleon. Have fun experimenting and see what else you can create!