To make pollen in Little Alchemy 2, you'll need to combine the element Air with an element related to plants, such as Grass, Tree, Flower, or Bush. Air + Grass = Pollen. Air + Tree = Pollen. Air + Flower = Pollen. Air + Bush = Pollen. After that you can take the pollen and use it on other elements to craft a variety of items. For example, you can combine pollen with Honey to create a Bee, or combine pollen with Fire to create a Butterfly.